Artificial Intelligence Tools for Scaling Up of High Shear Wet Granulation Process
نویسندگان
چکیده
منابع مشابه
Scale-up studies on high shear wet granulation process from mini-scale to commercial scale.
A newly developed mini-scale high shear granulator was used for scale-up study of wet granulation process from 0.2 to 200 L scales. Under various operation conditions and granulation bowl sizes, powder mixture composed of anhydrous caffeine, D-mannitol, dibasic calcium phosphate, pregelatinized starch and corn starch was granulated by adding water. The granules were tabletted, and disintegratio...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2017
ISSN: 0022-3549
DOI: 10.1016/j.xphs.2016.09.022